713贵宾会(中国·VIP认证)检测线路·Maigoo百科

主要学习、工作经历

2002.10—2006.06 浙江大学—高分子材料与工程学 工学学士
(Polymer Materials and Engineering, Zhejiang University, Bachelor of Engineering)
2006.09—2012.07 中科院长春应用化学研究所—高分子化学与物理 理学博士
(Polymer Chemistry and Physics, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences Doctor of Philosophy)
2012.08—2016.03 日本理化学研究所—纳米医学与工学材料 博士后
(Nano Medical Materials and Engineering, RIKEN, Japan Postdoctor)
2016.09-2020.12 长春理工大学—713贵宾会检测线路 助理研究员
(School of Materials Science and Engineering, CUST Assistant Professor)
2021.01 至今 长春理工大学—713贵宾会检测线路 副研究员
(School of Materials Science and Engineering, CUST Associate Professor)

主要教学工作

高分子化学与物理课程设计，复合材料，材料现代分析与测试技术综合训练

代表性科研项目

（1）2020-2022，含可热解离侧链的聚噻吩/碳纳米管复合薄膜的绿色加工及作为柔性热电材料的应用研究，吉林省科技发展计划，国际合作项目，负责人
（Green processing of single-walled carbon nanotubes using thermally cleavable polythiophenes for flexible thermoelectric films，Jilin Provincial science and technology development program）
（2）2019-2021, 具有刚性疏水主链的阳离子聚噻吩衍生物作为核酸类药物载体的研究, 国家自然科学基金—青年基金, 负责人
(Development of cationic polythiophene derivatives with hydrophobic and rigid rod-like backbones for nucleic acid-based drug delivery, NSFC)
（3）2017-2019, 基于聚噻吩的新型核酸类药物载体的研究, 长春理工大学自然基金—青年基金, 负责人
(Synthesis and application of polythiophene-based drug delivery systems for gene transfection, CUST)
（4）2011-2013，具有电活性的聚酯酰胺生物可降解高分子的合成及应用，国家自然科学基金—面上项目, 参与人
(Synthesis and application of biodegradable and electroactive poly(ester amide) materials, NSFC)

代表性论文或专利

1. He, P.;  Ren, X.;  Zhang, Y.;  Tang, B.; Xiao, C., Recent advances in sulfur dioxide releasing nanoplatforms for cancer therapy. Acta Biomaterialia 2024, 174, 91-103.

2. Tang, B.;  Zhang, Y.;  Liu, X.;  Wang, Y.; He, P., A Novel Polyamino Acid Sulfur Dioxide Prodrug Synergistically Elevates ROS with β-Lapachone in Cancer Treatment. Journal of Pharmaceutical Sciences 2023 (doi: 10.1016/j.xphs.2023.11.027).

3. Zhang, Y.;  Liu, X.;  He, P.;  Tang, B.;  Xiao, C.; Chen, X., Thiol-Responsive Polypeptide Sulfur Dioxide Prodrug Nanoparticles for Effective Tumor Inhibition. Biomacromolecules 2023, 24 (9), 4316-4327.

4. Zhang, Y.;  Zhang, H.;  Wang, Y.;  Ji, Y.;  Wang, F.; He, P., A Novel Cu(II) Loaded Polypeptide SO2 Prodrug Nanoformulation Combining Chemodynamic and Gas Anticancer Therapies. Macromolecular Bioscience 2023, 2300429.

5. Yin, Z.;  Zhang, H.;  Wang, Y.;  Wu, Y.;  Xing, Y.;  Deng, L.;  He, P.; Guo, X., Superior Carrier Mobility Enabled by the Charge Channel Leads to Enhanced Thermoelectric Performance in BiCuSeO Composites. Small 2023, 19 (50), 2304430.

6. Sun, Y. T.;  Zhang, Y.;  Guo, X.;  Wang, Y. P.;  He, P.; Xiao, C. S., Oxidation Responsive PEGylated Polyamino Acid Bearing Thioether Pendants for Enhanced Anticancer Drug Delivery. Macromolecular Bioscience 2023, 23 (3), 2200498.

7. Zhang, H.;  Zhang, C.;  Gregory, D. H.;  Yin, Z.;  Wang, Y.;  He, P.; Guo, X., A review of pressure manipulating structure and performance in thermoelectrics. Journal of Physics D: Applied Physics 2023, 56 (18), 183001.

8. He, P.;  Tang, B. T.;  Li, Y. S.;  Zhang, Y.;  Liu, X. M.;  Guo, X.;  Wang, D.;  She, P.; Xiao, C. S., Effective Oxidation-Responsive Polyester Nanocarriers for Anti-Inflammatory Drug Delivery. International Journal of Nanomedicine 2021, 16, 5053-5064.

9. Zhang, Y.;  Zhang, H.;  He, P.;  Yi, X.;  Liu, X.; Xiao, C., A PEGylated alternating copolymeric prodrug of sulfur dioxide with glutathione responsiveness for Irinotecan delivery. Journal of Materials Chemistry B 2021, 9 (1), 187-194.

10. Zhang, Y.;  Liu, X. M.;  Wang, X. P.;  He, P.;  Xiao, C. S.;  Yu, H. Y.; Chen, X. S., Nanoparticles Composed of PEGylated Alternating Copolymer-Combretastatin A4 Conjugate for Cancer Therapy. Macromolecular Bioscience 2021, 21 (8), 2100077.

11. Zhang, Y.;  He, P.;  Zhang, P.;  Yi, X.;  Xiao, C. S.; Chen, X. S., Polypeptides-Drug Conjugates for Anticancer Therapy. Advanced Healthcare Materials 2021, 10 (11) , 2001974.

12. He, P.;  Shimano, S.;  Salikolimi, K.;  Isoshima, T.;  Kakefuda, Y.;  Mori, T.;  Taguchi, Y.;  Ito, Y.; Kawamoto, M., Noncovalent Modification of Single-Walled Carbon Nanotubes Using Thermally Cleavable Polythiophenes for Solution-Processed Thermoelectric Films. ACS Appllied Materials and Interfaces 2019, 11 (4), 4211-4218.

13. Zhang, Y.;  He, P.;  Liu, X. M.;  Yang, H. L.;  Zhang, H. Y.;  Xiao, C. S.; Chen, X. S., A PEGylated alternating copolymer with oxidation-sensitive phenylboronic ester pendants for anticancer drug delivery. Biomaterials Science 2019, 7 (9), 3898-3905.

14. Zhang, Y.;  He, P.;  Liu, X. M.;  Zhang, H. Y.;  Yang, H. L.;  Xiao, C. S.; Chen, X. S., Synthesis of PEGylated alternating copolymer bearing thioether pendants for oxidation responsive drug delivery. European Polymer Journal 2018, 107, 308-314.

15. Shen, W.;  He, P.;  Xiao, C.; Chen, X., From Antimicrobial Peptides to Antimicrobial Poly(α-amino acid)s. Advanced Healthcare Materials 2018, 7 (20), 1800354.

 

授权专利 (Patents)：

(1) 何盼; 孙艺涛; 任婷婷; 万玉春; 李艳辉; 段潜 ; 一种含有硫醚基团的N-羧基环内酸酐及其制备方法和应用, 2023-8-8, 中国, 202210091688.3      

(2) 陈学思; 何盼；庄秀丽; 林琳; 汤朝晖; 胰岛素载药微球及其制备方法, 2013-04-10, 中国, 201110368851.8      

(3) 汤朝晖; 赵丽; 丁建勋; 何盼；肖春生; 庄秀丽; 陈学思 ; 一种胰岛素载药微球及其制备方法,2012-05-30, 中国, 201110023708.5      

 

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